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In Memoriam
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June 2017 Pulmonary Case of the Month

Robert Horsley, MD

Lewis J. Wesselius, MD 


Department of Pulmonary Medicine

Mayo Clinic Arizona

Scottsdale, AZ USA


History of Present Illness

A 61-year-old woman presented to the emergency department for 3 days of fevers up to 102º F, malaise, and progressive shortness of breath. Her symptoms started immediately after he last naltrexone injection for alcohol use disorder.

Past Medical History, Social History and Family History

  • Alcohol use disorder
  • Treated with monthly naltrexone injections, received 3 doses total, and gabapentin
  • No other previous medical issues
  • Nonsmoker

Physical Examination

  • Vital signs: Pulse 100, BP 108/90, respiratory rate 34, SpO2 93% 10L non-rebreathing mask
  • Cyanotic on room air
  • Lungs clear


A portable chest x-ray was performed in the emergency department (Figure 1).

Figure 1. AP chest radiograph taken in the emergency department.

A thoracic CT scan was performed (Figure 2).

Figure 2. Representative images from thoracic CT in lung windows.


  • CBC showed a white blood cell count of 12,000 cells/mcL.
  • The differential showed a left shift.
  • Lactate was 5.2 mmol/L

Which of the following is (are) true? (Click on the correct answer to proceed to the second of five pages)

  1. A lactate level of 5.2 can be a normal finding in a critically ill patient
  2. Her symptoms are likely an allergic reaction to naltrexone
  3. The most likely diagnosis is an atypical pneumonia
  4. 1 and 3
  5. All of the above

Cite as: Horsley R, Wesselius LJ. June 2107 pulmonary case of the month. Southwest J Pulm Crit Care. 2017;14(6):255-61. doi: PDF

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