Ultrasound For Critical Care Physicians: Where Did the Bubbles Go?

A 35-year-old woman with factor V Leiden deficiency on chronic anticoagulation therapy and a history of multiple deep vein thrombosis, pulmonary embolism and transient ischemic attacks presented for an evaluation of dyspnea. An echocardiogram with agitated saline contrast (bubble study) was performed (Figure 1).

Figure 1. Apical 4 chamber video taken from bubble study.

What is the best explanation for the findings in the video?

1. Intra-atrial right to left shunting
2. Normal bubble study
3. Pulmonary arterial-venous malformation
4. Ventricular septal defect

Reference as: Natt B, Snyder L, Lax D. Ultrasound for critical care physicians: where did the bubbles go? Southwest J Pulm Crit Care. 2014;9(2):91-3. doi: http://dx.doi.org/10.13175/swjpcc100-14 PDF

August 2014 Critical Care Case of the Month: The Beans Are Done

Theodore Loftsgard RN, CNP

Zanele Manaka R.R.T., C.R.T.

Jocelyn Coy R.N.

Jared J. Jones, Pharm.D., R.Ph.

Division of Critical Care

Mayo Clinic

Rochester, Minnesota

Case Presentation

A 68-year-old woman was admitted to the ICU due to acute renal failure in setting of ovarian cancer recurrence.

She reports a two week history of abdominal pain with increased, loose ileostomy output, nausea, one episode of vomiting of food returns, and profound increasing generalized weakness. She states she has been voiding urine in normal frequency. She took her most recent dose of Xarelto 20mg the evening prior to presentation.

On ICU arrival, she was alert and oriented but pale and underweight with dry mucous membranes. She reported 2/10 generalized abdominal pain. Her blood pressure was stable. 

PMH

March 2013: Diagnosed with stage IIIC metastatic ovarian cancer.  She underwent extensive abdominal surgery including radical hysterectomy, diverting loop ileostomy and cholecystectomy.  Final pathology: grade 3 serous carcinoma involving omentum, descending colon, cecum and terminal ileum, both ovaries with implants on bilateral tubes and uterine serosa, right pelvic side wall, right diaphragm, 3 right paraaortic lymph nodes, and gallbladder. 

April 2013: She developed thrombus of the bilateral peroneal veins, left posterior tibial vein, and right soleal veins and was started on Lovenox She was recently transitioned to rivaroxaban (Xarelto).

February 2014: abdominal ultrasound showed numerous small, hypoechoic nodules and lesions throughout the liver which were worrisome for metastatic disease. She presented to the clinic today for a second opinion.

Current Medications

1. Fentanyl 100 mcg/hr patch 72 hour 1 patch transdermally every 3 days
2. Ibuprofen PRN
3. Oxycodone PRN
4. Rivaroxaban (Xarleto®) 20 mg daily
5. Sertraline (Zoloft®) 25 mg daily

Past Medical/Surgical History

    Past Medical History   

1. Craniocervical dystonia receives Botox injections.
2. Ovarian cancer

    Past Surgical History  

1. Appendectomy at 8 years old.
2. Tonsillectomy.
3. Laparoscopy in 1983 for infected Dalkon Shield.
4. L5 bulging disk surgery in the 1990s.
5. Total abdominal hysterectomy, bilateral salpingo-oophorectomies, cholecystectomy, lymphadenectomy, and tumor debulking for ovarian cancer March 2013.

Physical Exam

Vital signs: height 164.3 cm, weight 42.90 kg, BSA(G) 1.40 M², BMI 15.892 Kg/M², temperature 36.4 °C, respiratory rate 13 breaths/minute, blood pressure 148/77 mmHg.  pulse 64/minute.  SpO2 98% on room air.

Heart: S1, S2 with no murmur, click, rub. Sinus rhythm, rate 64, no ectopy.

Lungs: Respirations symmetrical and easy with bilateral breath sounds clear to auscultation.

Abdomen: Slightly firm, nondistended, mild tenderness to palpation, bowel sounds present. Ostomy pink with dark brown liquid output in bag.

Electrocardiogram

Figure 1. ICU admission electrocardiogram.

Ultrasonography

Figure 2. Panel A: Static image from abdominal ultrasound of inferior vena cava. Panel B: Static image from abdominal ultrasound showing longitudinal axis of left kidney. Panel C: Static image from abdominal ultrasound showing longitudinal axis of right kidney. Lower panel: movie of ultrasound of inferior vena cava.

Which of the following is (are) true? (Click on the correct answer to proceed to the next panel)

1. The electrocardiogram shows tall, peaked T waves
2. The inferior vena cava is collapsed suggesting volume depletion
3. There is hydronephrosis of the left kidney
4. There is hydronephrosis of the right kidney
5. All of the above

Reference as: Loftsgard TO, Manaka Z, Coy J, Jones JJ. August 2014 critical care case of the month: the beans are done. Southwest J Pulm Crit Care. 2014;9(2):72-82. doi: http://dx.doi.org/10.13175/swjpcc087-14 PDF

Ultrasound for Critical Care Physicians: Cardiogenic Shock-This Is Not a Drill

Ramakrishna Chaikalam, MD 

Shozab Ahmed, MD

Division of Pulmonary, Critical Care and Sleep

University of New Mexico

Albuquerque, NM

A 45-year-old woman with no significant past history developed gradual onset of shortness of breath and cough over 1 week. She presented to the emergency department. Her initial chest x-ray showed an enlarged heart and bilateral pulmonary edema. The patient became progressively hypotensive and hypoxic and was intubated. Transthoracic echocardiography is shown below (Figure 1).

Figure 1. Transthoracic echocardiogram in the para-sternal long axis view of the heart.

What intra-cardiac device in the left ventricle is pictured on the image? (Click on the correct answer to proceed to the next panel)

1. Amplatz closure device of atrial septal defect
2. Extracorporeal membrane oxygenator (ECMO) cannula
3. Impella device
4. Intra-aortic balloon pump
5. Pacemaker lead

Reference as: Chaikalam R, Ahmed S. Ultrasound for critical care physicians: cardiogenic shock-this is not a drill. Southwest J Pulm Crit Care. 2014;9(1):27-9. doi: http://dx.doi.org/10.13175/swjpcc091-14 PDF

July 2014 Critical Care Case of the Month: There Is Still a Role for Physical Examination

Robert A. Raschke, MD 

Banner Good Samaritan Medical Center

Phoenix, AZ

History of Present Illness

A 90-year-old woman was the seatbelt-restrained driver in a low speed frontal motor vehicle collision with airbag deployment, after she accidentally hit the gas instead of the brake. In the emergency room, the patient’s main complaint was right shoulder pain. On ER physical exam, she had sternal ecchymosis consistent with “seatbelt sign”. Her right shoulder was said to be tender, but the mechanism of injury to the right shoulder was unclear since her drivers-side seatbelt would been in contact with her left rather than right shoulder. Her right upper extremity was said to be “weak secondary to pain”. Further neurological examination was noted to be difficult due to “patient crying out in pain and anxiety”, but it was noted that she could lift both legs off the bed. Her left knee was echymotic. Cardiac auscultation revealed irregularly irregular rhythm.

PMH

• Chronic atrial fibrillation
• Coronary artery disease
• Hypertension

Medications

• Warfarin
• Aspirin
• Clonidine
• Metoprolol

Labs performed in the emergency room showed an INR 1.9. Radiographs demonstrated a normal right shoulder and a left patellar fracture. CT scans of the cervical spine and chest showed no bony abnormalities. An incidental 4 cm thoracic aortic aneurysm was noted. CT of the brain showed periventricular white matter hyperlucencies consistent with small vessel disease. The patient became a bit drowsy after receiving narcotic analgesia in the emergency room and was transferred to the medical ICU for management of pain and delirium.

ICU Physical Examination

In the medical ICU the patient was alert, and seemed much younger than 90 years of age, with a sharp wit. She complained of 10/10 shoulder pain at rest which occasionally made her wince, cry out in pain and move her shoulder – however, she said there was no position in which her shoulder did not hurt. There were no ecchymosis of the shoulder, and it could be passively abducted and rotated without worsening the pain. The initial neurological examination was cursory and unrevealing because the patient was distracted by pain, and her left leg was immobilized.  A short time later the nurse reported that she felt the patient’s right leg was weak and the neurological exam was repeated. Strength in the patient’s right leg was 1/5, her left leg was immobilized, but ankle extension was 5/5. She could not cooperate well with strength testing of her painful right arm, but her right grip was 2/5 with a normal strength in her left arm and hand. Toes were down-going and reflexes were generally hypoactive. She was not aphasic. Neurology was consulted.

Which of the following is true in regards to this patient’s neurological findings? (Click on the correct answer to proceed to the next panel)

1. A cervical spinal cord injury could explain these findings
2. A seat belt injury of the left carotid artery could have resulted in traumatic dissection and subsequent stroke
3. Right hemiparesis without aphasia could represent a lacunar stroke
4. They might represent a cardio-embolic stroke related to her history of atrial fibrillation
5. All of the above

Reference as: Raschke RA. July 2014 critical care case of the month: there is still a role for physicial examination. Southwest J Pulm Crit Care. 2014;9(1):8-14. doi: http://dx.doi.org/10.13175/swjpcc086-14 PDF

Ultrasound For Critical Care Physicians: Neutropenic Patient With Fever and Shortness of Breath

Erik Kraai MD

Michel Boivin MD

Division of Pulmonary / Critical Care and Sleep

University of New Mexico

Albuquerque, NM

A 63 year old female with a history of acute myelogenous leukemia presents with shortness of breath, fever and hypotension to the ICU. She is in septic shock on norepinephrine, and has been treated on the oncology unit with vancomycin, cefepime, acyclovir and voriconazole. She has been neutropenic for 1 month. The patient develops a progressive right lower chest opacity. This opacity has progressed in spite of antibiotics and antifungals. The portable AP chest radiograph is presented below (Figure 1). 

Figure 1. Portable AP of chest.

An ultrasound of the right chest was performed for further evaluation of the opacity (figure 2). 

Figure 2. Ultrasound of right hemithorax.

Question: What pathology does the ultrasound reveal in the right hemithorax? (Click on the correct answer to proceed to the next panel)

1. Air filled cavity
2. Chest wall abscess
3. Fractured ribs
4. Pleural effusion and suspected empyema
5. Simple consolidation

Refernece as: Kraai E, Boivin M. Ultrasound for critical care physicians: neutropenic patient with fever snd shortness of breath. Southwest J Pulm Crit Care. 2014;8(6):330-3. doi: http://dx.doi.org/10.13175/swjpcc073-14 PDF