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4. Observation with follow-up

There are 3 types of pulmonary amyloidosis (1,2):

• Nodular pulmonary amyloidosis;
• Diffuse alveolar-septal amyloidosis;
• Tracheobronchial amyloidosis.

Nodular pulmonary amyloidosis  is often an incidental finding on chest imaging and usually represents localized immunoglobulin light chain or mixed immunoglobulin light chain/heavy chain amyloidosis. The mean age of patients is 67 with a male/female ratio of 3:2.  Nodular amyloidosis usually presents at peripheral subpleural locations of variable size and can be bilateral.  Usually the nodules are small, but cases up to 15 cm have been reported.

Which of the following disease(s) have been associated with nodular pulmonary amyloidosis? (Click on the correct answer to be directed to the sixth and final page)

1. Lymphoma
2. Adenocarcinoma of the lung
3. Sjogren’s syndrome
4. 1 and 3
5. All of the above

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