Correct!
4. 1 and 3
Some studies suggest an association with underlying lymphoproliferative disorder in the spectrum of extranodal marginal zone lymphoma of mucosa associated lymphoid tissue (MALT lymphoma) (3). There also may be an association with Sjogren’s syndrome. In general, nodular amyloidosis is managed conservatively, with excision performed in some cases. Some patients will progress and develop systemic amyloidosis requiring chemotherapy. Unless systemic disease develops, the prognosis of nodular pulmonary amyloidosis is very good.
References
- Milani P, Basset M, Russo F, Foli A, Palladini G, Merlini G. The lung in amyloidosis. Eur Respir Rev. 2017 Sep 6;26(145):170046. [CrossRef] [PubMed]
- Khan NA, Bhandari BS, Jyothula S, Ocazionez D, Buryanek J, Jani PP. Pulmonary manifestations of amyloidosis. Respir Med. 2023 Nov-Dec;219:107426. [CrossRef] [PubMed]
- Grogg KL, Aubry MC, Vrana JA, Theis JD, Dogan A. Nodular pulmonary amyloidosis is characterized by localized immunoglobulin deposition and is frequently associated with an indolent B-cell lymphoproliferative disorder. Am J Surg Pathol. 2013 Mar;37(3):406-12. [CrossRef] [PubMed]
Home/Pulmonary