Correct!
3. VATS lung biopsy


Reinstituting her therapy seems unlikely to be helpful when 6 months of therapy was not. It also seems there is little to be gained from a repeat bronchoscopy. Therefore, a VATS lung biopsy was performed (Figure 3).

Figure 3. Representative photomicrographs of the patient’s VATS lung biopsy. A: At low magnification (H & E, 20X), scattered nodular granulomas (1-2 mm) are present in the peribronchial spaces. B: At higher magnification (H & E, 200X) a relatively well-formed nut non-necrotizing granuloma (right side) is present in the airspace adjacent to a small bronchiole (left of center).


What is the most likely diagnosis? (Click on the correct answer to be directed to the sixth of seven pages.)

  1. Coccidioidomycosis
  2. Granulomatosis with polyangiitis
  3. Hypersensitivity pneumonitis secondary to MAC
  4. Miliary tuberculosis
  5. Sarcoidosis

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