Correct!
1. MRI of the brain

Image-guided drainage of the new right pleural effusion is clearly indicated. The development of a new pleural effusion in the context of an unexplained ipsilateral pulmonary nodule, particularly given the tracer accumulation in the pleura at the 18FDG-PET scan (Figure 5), is a potentially worrisome situation, and therefore tissue sampling of the right lung nodule is advisable. As noted previously, tissue sampling by percutaneous transthoracic needle biopsy or surgical biopsy is appropriate; however, there is no indication for brain MRI.

The patient underwent percutaneous transthoracic needle biopsy (Figure 7), which only yielded scant blood, inflammatory cells, fibrotic material, and non-specific findings.

Figure 7. Image acquired during percutaneous transthoracic needle biopsy (A). The right pleural effusion is evident. Imaging immediately following the biopsy procedure shows a right pneumothorax (*, B).

Which of the following represents the most appropriate recommendation for the patient’s management? (Click on the correct answer to be directed to the thirteenth and final page)

  1. Bronchoscopy with transbronchial biopsy
  2. Cryobiopsy
  3. Intercostal arteriography
  4. Repeat percutaneous transthoracic needle biopsy
  5. Video-assisted thoracoscopic surgical lung biopsy

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