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Jan192021

6-Month Consequences Of COVID-19 in Patients Discharged from Hospital: A Cohort Study

Huang C, Huang L, Wang Y, et al. Lancet. 2021 Jan 16;397(10270):220-232. [CrossRef] [PubMed]

The long-term health consequences of COVID-19 remain largely unclear. In the largest follow-up study of COVID-19 patients 1733 of 2469 discharged patients with COVID-19 from Wuhan, China were enrolled after 736 were excluded. Patients had a median age of 57·0 (IQR 47·0-65·0) years and 897 (52%) were men. The follow-up study was done from June 16, to Sept 3, 2020, and the median follow-up time after symptom onset was 186·0 (175·0-199·0) days. Fatigue or muscle weakness (63%, 1038 of 1655), sleep difficulties (26%, 437 of 1655) and anxiety or depression (23%, 367 of 1617) of patients were the most common symptoms reported. Patients who were more severely ill during their hospital stay had more severe impaired pulmonary diffusion capacities and abnormal chest imaging manifestations, and are the main target population for intervention of long-term recovery. 

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