Correct!
5. The best course for treatment is not established
There is no established therapy for AIP. Of those listed, there is some evidence that mycophenolate might result in some improvement (6). She was begun on mycophenolate and showed some clinical improvement, no longer requiring oxygen at rest after 3 months. Her CT findings had also improved (Figure 4), but she still had restrictive changes on pulmonary function testing.
Figure 4. Representative images from repeat thoracic CT scan at 3 months follow-up.
References
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- Ryu AJ, Glazebrook KN, Samreen N, Bauer PR, Yi ES, Ryu JH. Spectrum of chronic complications related to silicone leakage and migration. Am J Med. 2018 Nov;131(11):1383-6. [CrossRef] [PubMed]
- Cordier JF. Cryptogenic organising pneumonia. Eur Respir J. 2006 Aug;28(2):422-46. [CrossRef] [PubMed]
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- McCoy SS, Mukadam Z, Meyer KC, Kanne JP, Meyer CA, Martin MD, Sampene E, Aesif SW, Rice LN, Bartels CM. Mycophenolate therapy in interstitial pneumonia with autoimmune features: a cohort study. Ther Clin Risk Manag. 2018 Nov 1;14:2171-81. [CrossRef] [PubMed]
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