Correct!
5. Prognosis with angiosarcoma is poor

Angiosarcoma is an uncommon tumor but can affect young adults as well as the old (3). It usually presents with multiple solid lung nodules or masses but can present with cavitating lesions or even ground glass opacities or consolidation (4). Most cases in the lung are thought to represent metastatic disease, however, primary pulmonary angiosarcoma has been reported although it is very rare (5). There is no standard therapy (3,5). Surgical resection, radiation, and chemotherapy have all been attempted. Surgery has been the mainstay for locally confined disease. Chemotherapy and radiotherapy often produce an initial response. Systemic administration of high doses of recombinant interleukin 2 (rIL‐2) also has been reported to be effective in primary angiosarcoma of the lung (6). However, regardless of the treatment prognosis usually remains poor. Median survival has been reported at 7 months (3).

References

  1. Azar MM, Hage CA. Laboratory diagnostics for histoplasmosis. J Clin Microbiol. 2017 Jun;55(6):1612-20. [CrossRef] [PubMed]
  2. Galgiani JN, Knox K, Rundbaken C, Siever J. Common mistakes in managing pulmonary coccidioidomycosis. Southwest J Pulm Crit Care. 2015;10(5):238-49. [CrossRef]
  3. Ravi V, Patel S. Vascular sarcomas. Curr Oncol Rep. 2013 Aug;15(4):347-55. [CrossRef] [PubMed]
  4. Tateishi U, Hasegawa T, Kusumoto M, Yamazaki N, Iinuma G, Muramatsu Y, Moriyama N. Metastatic angiosarcoma of the lung: spectrum of CT findings. AJR Am J Roentgenol. 2003 Jun;180(6):1671-4. [CrossRef] [PubMed]
  5. Ren Y, Zhu M, Liu Y, Diao X, Zhang Y. Primary pulmonary angiosarcoma: Three case reports and literature review. Thorac Cancer. 2016 Sep;7(5):607-13. [CrossRef] [PubMed]
  6. Palvio DH, Paulsen SM, Henneberg EW. Primary angiosarcoma of the lung presenting as intractable hemoptysis. Thorac Cardiovasc Surg 1987;35:105-7. [CrossRef] [PubMed]

Home/Pulmonary