Correct!
1,2,3,4 or 5.

This was to some extent a trick question. Histological analyses frequently reveal a pattern of NSIP overlapping with organizing pneumonia in Sjögren’s syndrome. Corticosteroids are the reference therapy for organizing pneumonitis. In refractory organizing pneumonia, immunosuppressive agents such as azathioprine, cyclosporine, infliximab and rituximab have been used but none are established therapy in Sjögren’s syndrome (5). Our patient opted for mycophenolate therapy with close observation since the tempo of her disease appeared to be relatively slow.

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References

1. Martin LJ. Tests to diagnose shortness of breath. WebMD. August 14, 2016. Available at: https://www.webmd.com/lung/breathing-problems-diagnosis#2 (accessed 8/13/18).
2. Pellegrino R, Viegi G, Brusasco V, et al. Interpretative strategies for lung function tests. Eur Respir J. 2005 Nov;26(5):948-68. [CrossRef] [PubMed]
3. Kumar A, Kotloff RM. Diagnostic approach to the adult with cystic lung disease. UpToDate. June 23, 2017. Available at: https://www.uptodate.com/contents/diagnostic-approach-to-the-adult-with-cystic-lung-disease (accessed 8/13/18).
4. Larsen BT, Colby TV. Update for pathologists on idiopathic interstitial pneumonias. Arch Pathol Lab Med. 2012 Oct;136(10):1234-41. [CrossRef] [PubMed]
5. Flament T, Bigot A, Chaigne B, Henique H, Diot E, Marchand-Adam S. Pulmonary manifestations of Sjögren's syndrome. Eur Respir Rev. 2016 Jun;25(140):110-23.  [CrossRef] [PubMed]

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