1. Active HBV infection

The positive surface antigen and positive core antibody are indicative of active hepatitis B infection, which can be either acute or chronic.

Additional laboratory evaluation revealed a C-reactive protein of 132 mg/dL and an erythrocyte sedimentation rate (ESR) of 45 mm/hr. Antinuclear antibody was negative as were antineutrophil cytoplasmic antibodies (ANCAs).

Abdominal ultrasound revealed slightly enlarged liver with normal echotexture. CT abdomen/pelvis showed the same with normal ducts and a normal pancreas without peripancreatic inflammation.

Which of the following is on your differential diagnosis? (Click on the correct answer to proceed to the fourth of six pages)

  1. Eosinophilic granulomatosis with polyangiitis
  2. Granulomatosis with polyangiitis
  3. Microscopic polyangiitis
  4. Polyarteritis nodosa
  5. 1 and 3

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