Correct!
1. Acquired immunodeficiency syndrome (AIDS)

Isobutyl nitrite and other alkyl nitrites were first used to treat angina pectoris. In the late 1970s these drugs emerged as part of the drug subculture of the disco and club scene as a sexual orgasm intensifying agent (1). The drugs were particularly popular amongst homosexual men. Early descriptions of the acquired immune deficiency syndrome implicated the substances due to their frequent use amongst afflicted individuals (2,3). When causation of the alkyl nitrites for AIDS was disproven, the strong association led to confounding theories of pathogenesis. Today, alkyl nitrites remain legal to possess.

Which of the following adverse effects has (have) not been described with the inhalation of alkyl nitrites? (Click on the correct answer to proceed to the fifth of six pages)

  1. Acute respiratory distress syndrome
  2. Methemoglobinemia
  3. Bronchospasm
  4. 1 and 3
  5. All of the above

Home/Critical Care