Correct!
5. All of the above

Spontaneous coronary artery dissection is a rare cause of acute coronary syndrome with a spectrum of clinical presentations ranging from chest pain to ST-elevation myocardial infarction to ventricular fibrillation and sudden death (4). It typically affects a younger, otherwise healthy, female population. Initial mortality is fairly low, however ten-year rates of major adverse cardiac events is estimated at 47%. Fibromuscular dysplasia, connective tissue disorders such as Ehlers-Danlos or Marfan syndrome, and cocaine use have all been associated and are potentially causative factors.

Surgical versus medical management was discussed. Percutaneous intervention carried too great a risk for further progression of the dissection. Coronary artery bypass graft surgery carried a high risk of early graft failure due to competitive flow. Given these potential complications, medical management was pursued.

References

  1. Hazinski MF, Nolan JP, Aickin R, et al. Part 1: Executive summary: 2015 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations. Circulation. 2015;132(16 Suppl 1):S2-39. [CrossRef] [PubMed]
  2. Dave J, Bessette M, Setnik G, Gaeta TJ, Lakhia R. Torsades des pointes. Medscape (2015). Available at: http://emedicine.medscape.com/article/1950863-overview (accessed 1/26/16).
  3. Yap YG, Camm AJ Drug induced QT prolongation and torsades de pointes. Heart. 2003;89(11):1363–72. [CrossRef] [PubMed]
  4. Tweet MS, Hayes SN, Pitta SR, et al. Clinical features, management, and prognosis of spontaneous coronary artery dissection. Circulation. 2012;126(5):579-88. [CrossRef] [PubMed]

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