Correct!
5. Voriconazole
First line treatment for invasive aspergillosis is now voriconazole (2). If the patient is intolerant or unresponsive to voriconazole, a lipid formulation of amphotericin B may be added. An echinocandin (caspofungin, micafungin) may be added for 10-14 days before stepping down to monotherapy.
Our patient was treated with voriconazole and was improving.
References
- Gadkowski LB, Stout JE. Cavitary pulmonary disease. Clin Microbiol Rev. 2008;21(2): 305-33. [CrossRef] [PubMed]
- Walsh TJ, Anaissie EJ, Denning DW, Herbrecht R, Kontoyiannis DP, Marr KA, Morrison VA, Segal BH, Steinbach WJ, Stevens DA, van Burik JA, Wingard JR, Patterson TF; Infectious Diseases Society of America. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis. 2008;46(3):327-60. [CrossRef] [PubMed]
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