Correct!
3. Secondary amyloidosis
Figure 3 shows bilateral atrophic kidneys consistent with chronic renal disease indicating secondary amyloidosis as the best answer. Secondary amyloidosis is characterized by deposition of an acute phase protein due to chronic infection and/or inflammation and usually affects the kidneys first. The patient did not have a history of multiple myeloma and therefore, primary amyloidosis, which is characterized by amyloid light chain deposition, is not the correct answer. Additionally, familial amyloidosis is identified as a genetic mutation responsible for the coding and production of the protein transthyretin; no information obtained by the history or the image points to familial amyloidosis as the correct answer.
Figure 4. Representative images from serial CT scans. Panel A: The initial chest CT Panel B: 8 weeks after the initial chest CT. Panel C: 12 weeks. Panel D: 5 months.
Which of the following choices most closely characterizes the association between the type of pulmonary amyloidosis and the entity associated with it? (Click on the correct answer to proceed to the next panel)