Correct!
4. Patchy consolidation

Posteroanterior chest radiograph demonstrates patchy airspace disease predominately in the form of right middle and right lower lobe consolidation.  Findings are most concerning for pneumonia.  Patient also has cardiomegaly suggesting heart disease or volume overload.  A right subclavian vein stent suggests underlying renal disease.

A thoracic CT was performed for further evaluation (Figure 2).

Figure 2. Panel A: representative lung window. Panel B: representative soft tissue window.

In addition to right middle lobe and right lower lobe consolidation/pneumonia, multiple pulmonary cysts were noted.  Many of these cysts are associated with calcified pulmonary nodules.  In addition, the left ventricle is diffusely thickened. 

Given the finding of pulmonary cysts, which of the following diagnoses is least likely favored as part of the differential diagnosis in this patient? (Click on the correct answer to proceed to the next panel)

  1. Langerhan’s cell histiocytosis (LCH)
  2. Lymphangioleiomyomatosis (LAM)
  3. Lymphocytic Interstitial pneumonia (LIP)
  4. Pulmonary nodular amyloidosis
  5. Pulmonary sarcoidosis

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