Correct!
2. The 18FDG-PET scan shows elevated glucose utilization within peribronchial and mediastinal lymph nodes as well as the lung parenchymal abnormalities

The 18FDG-PET scan shows elevated glucose utilization within peribronchial and mediastinal lymph nodes as well as the lung parenchymal abnormalities. The areas of abnormal tracer utilization do not correspond to areas of normally metabolically active tissue, such as brown fat- such “normally” metabolically active tissues are often seen in the base of the neck near the cervical-thoracic junction and occasionally within the inter-atrial septum, as well as the left ventricular myocardium (the latter is visible in Figure 3). The areas of abnormal tracer utilization show fairly homogeneous, intense activity; no central photopenic defects [which may be seen when a metabolically lesion is centrally necrotic] are present.

Which of the following represents an appropriate step for the evaluation of this patient? (Click on the correct answer to proceed to the seventh of nine panels)

  1. Bronchoscopy with transbronchial biopsy
  2. Mini-thoracotomy
  3. Percutaneous fine needle aspiration biopsy
  4. Video-assisted thoracoscopic surgical biopsy
  5. 1 or 3

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