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3. Thoracic CT shows multiple, bilateral non-calcified pulmonary nodules and peribronchial and mediastinal lymph node enlargement

The contrast-enhanced CT shows multiple, bilateral non-calcified pulmonary nodules and peribronchial and mediastinal lymph node enlargement. The peribronchial lymphadenopathy is best visualized on the left, and the largest pulmonary lesion, non-calcified, is located in the anterior basal left lower lobe, abutting the left major fissural surface. The nodules ad masses are solid; no evidence of cavitation is seen. The lucency seem within the larger lesions represent air bronchograms, not necrosis with cavitation. Emphysema is present, but there is no evidence of cystic lung disease, nor are significant pleural abnormalities present. The anterior mediastinum shows a subcentimeter lymph node, but no dominant mass. Middle mediastinal abnormalities- presenting paratracheal and left tracheobronchial angle lymphadenopathy- are present, with a prominent anterior mediastinal lymph node, but no dominant mass is seen.

Which of the following is the most appropriate next step for the further evaluation of this patient? (Click on the correct answer to proceed to the fifth of nine panels)

  1. 18FDG-PET
  2. 68Ga-citrate scintigraphy
  3. Contrast-enhanced thoracic CT using a pulmonary nodule protocol
  4. Serial CT assessment for nodule growth
  5. Thoracic MRI

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